With a breakthrough medical procedure, there is hope for retina-damaged patients. At the Universidad Compultense de Madrid (UCM), researchers published the findings in The Journal of Neural Engineering.
The artificial retina is a cell therapy for the reconstruction of the damaged retina by implanting healthy cells in the patient's eye. The cells of the artificial retina adhere to very thin silk fibroin biofilms and are covered by a gel during eye surgery. The special silk fibers help to build this artificial retina which have the mechanical characteristics of the membrane of Bruch, the layer of cells supported by the neural retina.
"The biohybrid retina is a cell therapy for the reconstruction of the damaged retina by implanting healthy cells in the patient's eye," says Fivos Panetsos, director of the UCM's Neuro Computers Group and member of the Clínico San Carlos de Madrid Institute of Health Research (IdISSC).
The UCM researchers and director, published in Journal of Neural Engineering, added that The transplanted retina also contains mesenchymal cells that function as producers of neuroprotective and neuroreparative molecules and facilitate functional integration between implanted and patient cells"
Age-Related Macular Degeneration (AMD) is a neurodegenerative disease that causes a progressive loss of central vision. It is the leading cause of irreversible vision loss in people over 65 years of age and affects more than 196 million people. The cells of the artificial retina adhere to very thin, 100% biocompatible silk fibroin biofilms, which is covered by a gel that protects them during eye surgery and enables them to survive for the time that they need to be integrated into the tissue around them after transplantation.
AMD is a neurodegenerative disease that causes progressive central vision loss and blindness at their most advanced stage of development. AMD is a neurodegenerative disease. Driven by heterogeneous, complex and still poorly understood mechanisms, it has the greatest impact on over 196 million people world wide, resulting in irreversible vision loss in people over 65. Current treatments can only ease symptoms and decelerate the progression of the disease. AMD is an incurable disease.